产品货号:
Z10570
中文名称:
ACBD3抗体
英文名称:
Anti-ACBD3 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ACBD3 Antibody |
指标别名 | ACBD3;GCP60;GOCAP1;Golgi phosphoprotein 1;Golgi resident protein GCP60;GOLPH1;PAP7 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | ELISA,WB |
基因名称 | ACBD3 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | GOLPH1 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human GOLPH1.The immunogen is located within amino acids 50 - 100 of GOLPH1. |
计算分子量 | 61kDa |
成分 | GOLPH1 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | GOLPH1 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | GOLPH1,also known as GCP60,was initially identified as a Golgi protein that can interact with the integral membrane protein giantin and is thought to be involved in the maintenance of the Golgi structure.GOLPH1 has also been shown to interact with other Golgi proteins such as Golgin-160,a Golgi protein that can be cleaved by caspases-2,-3,and -7,leading to the nuclear localization of Golgin-160.GOLPH1 interaction with the Golgin-160 fragments is stronger than that with the intact Golgin-160,with its interaction regulated by the oxidation state of Cys-463 within GOLPH1,suggesting that the nuclear localization of the caspase-cleaved Golgin-160 fragments is a highly coordinated event.GOLPH1 has also been found to interact with Numb,a cytosolic signaling protein that mediates asymetric cell division of neural progenitor cells to a daughter progenitor cell and a neuron,suggesting that Golgi fragmentation and reconstitution during the cell cycle differentially regulate Numb signaling through changes in GOLPH1 subcellular distribution and may couple cell fate with cell cycle progression. |
Uniprot ID | Q9H3P7 |
基因名全称 | Acyl-Coenzyme A binding domain containing 3 |
蛋白名全称 | Acyl-Coenzyme A binding domain containing 3 |
推荐稀释比 | GOLPH1 antibody can be used for detection of GOLPH1 by Western blot at 1 ~ 2μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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